Cyclodextrin Based Spectral Changes

Thermodynamic, spectral and antimicrobial activity of inclusion complexes of acridone and its oxime with β-cyclodextrin

One of the methods to enhance bio-accessibility of drugs like Acridone and its oxime is toform inclusion complexes with β-cyclodextrin. The formation of such complexes has beenconfirmed by changes in spectral characteristics and melting point data. The aqueous phasesolubility studies reveal 1:1 stoichiometry between the compound and, β-cyclodextrin. The studyof thermodynamic parameters like ΔG,...

Inclusion Complexes of Promethazine with Monochlorotriazinyl-β-cyclodextrin

Formation of inclusion complexes of monochlorotriazinyl-β-cyclodextrin with promethazine was studied, for establishing the optimal conditions of their formation, in view of subsequent grafting on cellulose textiles with potential medicinal use. The infrared spectral study of inclusion in solid state indicated that the complex can be even formed by physically mixing the two substances. By the co...

Inclusion compounds of lankacidin-group antibiotics with cyclodextrins.

Lankacidin-group antibiotics formed inclusion compounds with beta-cyclodextrin in molar ratios of about 1:1. These compounds showed remarkably improved water-solubility and stability in aqueous solutions. The structure of the inclusion compounds of lankacidin A is proposed based on the facility of their inclusion with beta-cyclodextrin and the results of 1H NMR spectral studies.

Modeling and Optimization of β-Cyclodextrin Production by Bacillus licheniformis using Artiï‌cial Neural Network and Genetic Algorithm

Background: The complexity of the fermentation processes is mainly due to the complex nature of the biological systems which follow the life in a non-linear manner. Joined performance of artificial neural network (ANN) and genetic algorithm (GA) in finding optimal solutions in experimentation has found to be superior compared to the statistical methods. Range of applications of β-cyclodextrin (...

The Determination of the Stoichiometry of Cyclodextrin Inclusion Complexes by Spectral Methods: Possibilities and Limitations